Equipment profile · Cynosure
Cynosure PicoSure Pro: Price, Specs, FDA Clearance and Alternatives
PicoSure Pro is Cynosure’s 755 nm picosecond laser for practices offering pigment treatments and skin revitalization, with tattoo removal as an option. A Focus lens array handles the revitalization work, and 532 nm and 1064 nm add-ons extend tattoo colors.
The short answer
PicoSure Pro’s 755 nm laser is FDA cleared for tattoos and benign pigmented lesions, including melasma and nevus of Ota. With the Focus array, it’s also cleared for acne scars and wrinkles in skin types I to IV. FDA summaries from 2021 and 2026 report no technological changes from the original PicoSure, and Cynosure doesn’t publish prices.
Who should buy a PicoSure Pro?
Shortlist it if
- Pigment and skin revitalization are your main services, and tattoo removal is a bonus.
- Your providers want the Focus lens for acne scar and wrinkle treatments.
- You’ll add the 532 nm or 1064 nm delivery if you market multicolor tattoo removal.
Our take: new PicoSure Pro or a used PicoSure?
Compare them on configuration and support, not the name. Because the two share their laser parameters, a well-documented used PicoSure with the Focus lens is a fair comparison point.
For a used unit, get the laser history, the included add-ons and Cynosure’s transfer and service terms in writing. For a new one, get the Focus lens and both tattoo add-ons priced in the original quote.
Document-based buying analysis. Not a NuWays MD hands-on test of this device.
PicoSure Pro specifications at a glance
Before you compare
| Specification | PicoSure Pro | What it means for your practice |
|---|---|---|
| Wavelength | 755 nm picosecond alexandrite; optional 532 nm and 1064 nm delivery systems | The add-ons decide whether you can market multicolor tattoo removal. |
| Handpieces | Zoom 2 to 6 mm and fixed 5, 6, 8 and 10 mm handpieces | |
| Lenses | Focus lens array for acne scars and wrinkles (skin types I to IV); flat lens for pigment | Focus treatments are the revitalization service. Confirm the lens is in the quote. |
| Turbo mode | A shortened pulse width for stubborn tattoos (manufacturer description) | |
| Pigment indications | 755 nm: tattoos and benign pigmented lesions, including nevus of Ota, Hori macules and melasma | Plan pigment protocols with your clinical lead. |
Sources: Cynosure Lutronic · FDA 510(k) K261570.
See it next to the alternativesSpecs, cleared uses and ownership questions in one table.
PicoSure Pro vs. PicoSure: what changed?
The FDA summaries for 2021 and 2026 report no changes to technological characteristics, and Cynosure says the Pro has the same parameters. The 2026 clearance updated some indications.
| Feature | PicoSure Pro | PicoSure |
|---|---|---|
| Laser parameters | Same as PicoSure (Cynosure) | Same |
| FDA technological changes | None reported (2021, 2026) | Earlier clearances 2012 to 2018 |
| 532 nm indication | Tattoos and benign pigmented lesions, skin types I to III (2026) | Tattoos |
| Acne scars and wrinkles | 2 and 6 mm handpieces with the Focus array, skin types I to IV | Focus array |
Sources: FDA 510(k) K261570 · FDA 510(k) K210226 · Cynosure Lutronic.
What is the PicoSure Pro FDA cleared for?
Each 510(k) number links to its record in the FDA database. The summary PDFs are listed under Sources.
510(k) K261570 (PicoSure Workstation), cleared June 17, 2026. Product code GEX; Class II medical device. No changes to technological characteristics from K210226.
| Wavelength | Cleared uses (summarized) |
|---|---|
| 755 nm | Tattoos and benign pigmented lesions, including nevus of Ota, Hori macules and melasma; acne scars and wrinkles with the 2 and 6 mm handpieces and Focus array (skin types I to IV). |
| 532 nm | Tattoos and benign pigmented lesions on skin types I to III. |
| 1064 nm | Tattoos and benign pigmented lesions. |
Source: FDA 510(k) K261570.
510(k) K210226 (PicoSure Workstation), cleared March 30, 2021. Product code GEX; Class II medical device. No changes to technological characteristics from K173199.
Earlier clearances: K121346 (2012), K133364 and K140719 (2014), K143105 (2015), K160480 (2016) and K173199 (2018).
Source: FDA 510(k) K210226.
Clearance describes what a device may be marketed for; it does not predict results for a given patient.
PicoSure Pro clinical studies
Published studies we found on this system, its earlier models and related technology, each labeled by what it tested. Most are small, and some have manufacturer-affiliated authors, so use them to frame questions for the demo rather than as proof of results.
What we found: 1 on this system, 1 on an earlier model, 1 on related technology.
- This systemEvaluating the Picosecond 755-nm Alexandrite Laser With Diffractive Lens Array and Radiofrequency Microneedling for the Treatment of Atrophic Acne ScarsRF microneedling alone versus RF microneedling plus PicoSure with the Focus lens for acne scars. Adding PicoSure made no significant difference on blinded scales; both sides improved.
- Earlier model: PicoSure, before ProPicosecond laser with specialized optic for facial rejuvenation using a compressed treatment intervalPicoSure with the Focus lens for facial rejuvenation; side effects were mild and resolved within 48 hours.
- Related technology: PicoSure; model not statedEfficacy of PicoSure Laser in Treating Lichen Planus Pigmentosus and Pigmentary Demarcation Lines in Patients With Skin of ColorPicoSure for two pigment conditions in skin of color.
Links open the PubMed record.
How much does a PicoSure Pro cost?
| Price evidence | What we found |
|---|---|
| New system (manufacturer quote) | Cynosure does not publish prices, and we found no reliable public price for a new PicoSure Pro. Get a quote that lists add-ons and lenses. |
| Used (asking prices) | Not reviewed for this profile. On a used PicoSure or Pro, confirm the model, laser history, add-ons and Cynosure transfer terms. |
| Documented sale prices | None found. |
What ownership adds after purchase
| Cost area | What to confirm |
|---|---|
| Add-ons | The 532 nm and 1064 nm delivery systems are options; get both prices in the quote. |
| Lenses and handpieces | List which handpieces and lenses arrive, including Focus. |
| Eyewear | Rated eyewear for each wavelength, for staff and patients. |
| Service | Ask what the plan covers after the warranty, including the laser head. |
PicoSure Pro alternatives to compare
| Device | Technology | Why compare it |
|---|---|---|
| Candela PicoWay | Picosecond laser | Candela’s picosecond laser with 532, 730, 785 and 1064 nm and Resolve handpieces. |
| Candela Nordlys | SWT pulsed light and laser platform | Candela’s IPL and fractional platform for pigment and texture without tattoo removal. |
Different technologies are not interchangeable. Compare configurations, cleared uses and ownership costs before you book demos.
Questions to ask before you sign
- PicoSure Pro or an earlier PicoSure, and what are the serial number and laser history?
- Are the 532 nm and 1064 nm add-ons and the Focus lens included, and what do they cost later?
- Which handpieces and spot sizes are included?
- Is eyewear for each wavelength included?
- What does the warranty cover, and what does service cost from year two?
- How many training days are included, and what is the total with tax, freight, installation and financing?
Plan the purchase
Plan your PicoSure Pro purchase.
- Compare it side by side with its closest alternatives.
- Check what each quote includes: configuration, supplies, service and financing.
- Model the monthly payment against realistic treatment volume in the ROI calculator.
Other tattoo removal lasers to research
All tattoo removal lasers →More Cynosure equipment →Full equipment catalog →
Sources
Show all 3 sources
- Cynosure Lutronic: PicoSure Pro (November 7, 2026). Checked November 7, 2026.
- FDA 510(k) K261570: PicoSure Workstation (June 17, 2026). Checked November 7, 2026.
- FDA 510(k) K210226: PicoSure Workstation (March 30, 2021). Checked November 7, 2026.